Protein binder design

Design nanobody binders against your target

Submit a target structure or sequence and receive designed, screened and affinity-optimized nanobody candidates — fully automated, from submission to final structures.

Automatic end-to-end pipeline Structure or sequence input Ranked candidate binders

How it works

Submit your target

Provide a protein structure (PDB/mmCIF) or sequence (FASTA), and optionally the region the binder should target.

Automated design & optimization

Your job starts immediately on our compute server and runs through binder design, binding assessment and optimization.

Review your candidates

Each finished job reports the top candidates ranked by predicted binding confidence, with sequences and complex structures included.

Submit a design job

Target name

Used as your job reference, e.g. siteA

Target file

Protein structure (.pdb / .cif) or sequence (.fasta / .fa). Targets up to 500 residues.

or enter a database ID

UniProt / PDB ID

The structure is fetched automatically — the AlphaFold predicted structure for a UniProt ID, or the experimental structure for a PDB ID.

Binding site (optional)

Residues the binder should target, 1-based, e.g. 98..108 or 98..108,131..135. Leave empty to let the platform choose.

Notification email (optional)

We will email you a result summary when the job finishes.